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The U.S. Food and Drug Administration has approved Contrave (naltrexone hydrochloride and bupropion hydrochloride extended-release tablets) as treatment choice for chronic weight management in addition to a reduced-calorie diet and exercise. Using two separate drugs to shed weight can be very effective you will find combinations before the FDA now awaiting approval. When dealing with fat loss and the people that go through it one should err on the side of caution and permit the FDA do its job and demand some investigation be done so that the public recognizes the side effects and perils associated with the medications before we bring them. Keep in mind that drug companies come in business to generate money and that they would say everything to keep people on the medications. Researchers found that participants investing in this drug to get a year, lost weight within a month and have kept the extra weight off throughout the 56 weeks in the study. Contrave is really a combination of the drugs naltrexone and bupropion, which generally seems to reflect a whole new trend of weight-loss drugs which are made up of many active ingredient, which may make them more effective and safer. Combo-pilling could be the newest fad or in addition to this the newest to come under scrutiny and therefore it is just more publicly known lately, comb-pilling for losing weight has been around since the eighties. The biggest reason that employing a combination of pills is starting to become popular could be the fact that at the time of right now there are no long term prescription weightloss pills that have been licensed by the FDA other than orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications even though some of the combinations are already rejected or have yet to be approved by the FDA. Seizures can be a side effect with Contrave and shouldn't be taken in people with seizure disorders. The drug may also raise blood pressure level and heartrate, and must not be used in those with a history of cardiac arrest or stroke in the last six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy with the drug. The FDA also warned that Contrave can raise blood pressure and heartbeat and must stop used in patients with uncontrolled high blood pressure level, along with by a person with heart-related and cerebrovascular (circulatory dysfunction impacting your brain) disease. Patients using a history of cardiac arrest or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded through the clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, considering that the compound includes bupropion, Contrave comes using a boxed warning to alert medical researchers and patients to the increased risk of suicidal thoughts and behaviors associated with antidepressant drugs. The warning also notes that serious neuropsychiatric events happen to be reported in patients taking bupropion for smoking cessation. New UCLA study on smokers with mental, drug, and alcohol problems